Next-gen CAR-T cell therapy shows early promise in patients with refractory B-cell acute lymphoblastic leukemia

Safety and efficacy data from a Phase 1 multicenter study evaluating rapcabtagene autoleucel, an investigational next-generation CD19-directed CAR-T cell therapy produced in 48 hours using the T-CHARGE platform, shows a manageable safety profile and antitumor activity. The best overall response, defined as complete remission with complete remission or incomplete recovery of blood counts, was between…

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U.K. M&A is ‘on fire,’ Citi U.K. CEO says

U.K. M&A is running hot, driven by large-cap companies simplifying their businesses and overseas buyers targeting cash-generative British assets, Citi U.K. CEO Tiina Lee has told CNBC. Speaking with CNBC’s “Squawk Box Europe” in Canary Wharf Thursday, Lee said M&A was “on fire,” pointing to an ongoing push by major companies to streamline portfolios and…

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WSJ editorial board urges Trump not to fire Powell

The Editorial Board of the Wall Street Journal on Wednesday urged President Trump not to follow its threat to firing Federal Reserve President Jerome Powell, warning the results would be worse than the status quo. “It is often difficult to know when President Trump is serious about something, or only creates a distraction. But if…

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Pelosi on Trump-Iran deal: It's a gift to the Iranians

Representative Nancy Pelosi (D-Calif.) said Thursday that Americans “paid the price” for President Trump’s “mistake” in taking military action against Iran, calling the US-Iran Memorandum of Understanding (MOU) a “real gift to the Iranians.” “The current White House officials are tearing it apart and then moving forward with an agreement that it has failed… Source…

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