Boosting protein folding could protect insulin-making cells in diabetes

Origami masters transform simple sheets of paper into ornate sculptures. At the origin of life, proteins must fold into specific three-dimensional shapes before our cells can perform their biological functions. As prediabetes turns into diabetes, this folding process goes haywire. Misfolded and inactive proteins then accumulate in cells like pieces of paper tossed into an origami student’s recycling bin. This abnormal accumulation puts pressure on the cells responsible for insulin production.

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