Why the L-carnitine sport supplement is controversial

Sports are doses It is difficult to go away from If you like to exercise regularly. Even if you are not interested in them, there is one Good chance your gym There will be posters to increase their qualities or your sporty friend would like to talk to you about them.

It can be difficult to know if the supplement has to be taken because there is a lot Mixed information Outside there. L-carnitine is between more Controversial supplementWhile there is evidence of this Supports muscle recovery And exercise enhances performance, research has also shown that it can do it Contribution to heart disease,

One in New studyMy colleagues and I found that food may be possible to combat the negative effects of L-Carnitine. Pomegranate With this.

First of all, it is important to understand what L-carnitine is. Your body naturally produces small amounts of L-carnitine. It occurs in the kidneys, liver and brain.

When L-Carnitine was first recognized in humans in 1952, it was considered vitamin and was referred to Vitamin as BtAfter years of research on this compound, L-carnitine is now considered a semi-vitamin, because for most people, the human body itself can produce enough L-carnitine.

L-carnitine can be purchased as one dietary supplementBut nutrients are also added energy drink And some protein powder by manufacturers to increase and increase the value of its products. Manufacturers generally explicitly explain on the product if it contains L-carnitine-it is nothing that a company will try to hide.

Some foods naturally contain L-carnitine, such as Meat And small amounts Dairy productsL-carnitine is not fed to livestock, but it is present in muscle tissue. L-Carnitine was first found in meat in 1905. This is the reason that the name Carnitine Is derived from Latin word cornis, which means “meat.”

El-carnitine supplements harmful effects

It is not considered internally harmful. Yours Intestinal germ L-carnitine are blamed for risks.

L-carnitine supplements less than 20% Can be taken by Human body. Unabsorbed L-Carnitine travels to the gastrointestinal tract and reaches the colon. The home of the colon Germ trillionIncluding bacteria, viruses and fungi.

When the remaining 80% L-carnitine supplements come into the colon, germs start absorbing nutrients and they use it to produce something else: Trimethilamine (TMA). TMA is a compound that the human body can absorb efficiently, and it is where potentially Harmful effects L-carnitine supplements arise.

Once the body absorbs TMA, it goes through the blood flow to the liver. The liver changes TMA Trymethylmine n-oxide (TMAO). Research has shown that High level of TMAO Can contribute to blood cardiovascular disease,

For example, a research group at Cleveland Clinic in America Gave human participants A nutrient similar to L-Carnitine that is also converted into TMA by intestinal microbes. Researchers found that nutrients increased the risk of thrombosis (blood clots) among their participants.

L-carnitine is a beneficial nutrient in itself. When it is produced by our body, which occurs in the kidney, brain and liver, it is not metabolized by the intestine microbyota and does not convert to TMAOs. Your body can absorb L-carnitine more than meat compared to supplements, which makes it less harmful because it means that it ends in the colon.

Diet intervention can reduce harmful effects

In my team’s laboratory at the Quadram Institute in Norwich, England, we said what happens when the L-carnitine supplement reaches germs in the colon. We fed the culture of intestinal microbes with L-carnitine and measured TMA which were produced by microbes.

Then, we fed the culture of germs of the intestine with L-carnitine together PomegranateWhich is rich polyphenolsPolyphenols are plant compounds with antioxidants, antimicrobial and anti -inflammatory properties that can help you to keep you healthy and protect you from diseases.

The main polyphenols in pomegranate belong to a group AlgitaninsA type of polyphenol that is almost completely completely intact to the colon Intestine microbiotaWhen we measured TMA that intestinal microbes produced in another experiment, we saw very little TMA.

Our experiments in the lab suggest that a polyphenol-rich pomegranate extract can reduce microbial TMA production and eliminate the potentially harmful effects of L-carnitine supplements.

Our laboratory experiments showed that pomegranate extract can reduce the production of TMA. Allgitanine are also abundant in other fruits and nuts, such as raspberries and walnuts. Therefore, if you take L-carnitine supplements, our research suggests that it may be a good idea to include algitanin-rich foods in your diet. Eating more fruits and nuts can be good for your health, so it will probably be beneficial to join your diet anyway.

Our group is now carrying forward science outside the laboratory. We are testing How effective is pomegranate extract in human participants reduce TMAO production from L-Carnitine supplements. This study will tell us if it can be better to supplement the El-carnitine supplement with pomegranate extracts.

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