Next-gen CAR-T cell therapy shows early promise in patients with refractory B-cell acute lymphoblastic leukemia

Safety and efficacy data from a Phase 1 multicenter study evaluating rapcabtagene autoleucel, an investigational next-generation CD19-directed CAR-T cell therapy produced in 48 hours using the T-CHARGE platform, shows a manageable safety profile and antitumor activity. The best overall response, defined as complete remission with complete remission or incomplete recovery of blood counts, was between…

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Fantasy football Week 6 inactives: Ja’Marr Chase questionable (illness), Mac Jones expected to start for Brock Purdy

What should you start with? Who should you sit next to? To help you set your fantasy football lineups and avoid starting an offensive player who won’t be in the lineup, we’ll post fantasy-relevant updates and analysis here as NFL teams release their official inactive lists. Official Sunday inactive players begin arriving approximately 90 minutes…

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2 ways to protect your money in a rocky marriage

Before getting married, one of the topics you’ll want to discuss with your significant other is money, says Parima Pandkhou, divorce attorney at Wasser, Cooperman & Mandles. It’s important to talk about debt, income, budgeting, life goals — anything to do with your finances. “These are all very uncomfortable and heavy issues,” she says, “but…

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