Next-gen CAR-T cell therapy shows early promise in patients with refractory B-cell acute lymphoblastic leukemia

Safety and efficacy data from a Phase 1 multicenter study evaluating rapcabtagene autoleucel, an investigational next-generation CD19-directed CAR-T cell therapy produced in 48 hours using the T-CHARGE platform, shows a manageable safety profile and antitumor activity. The best overall response, defined as complete remission with complete remission or incomplete recovery of blood counts, was between…

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New therapies for advanced shoulder issues

Wear and tear, injury, certain medical conditions, and age can affect shoulder function. Often, surgery can be avoided, with many people responding well to non-operative treatments such as physical therapy or injections to reduce their pain and improve use of their shoulder. Sometimes, surgery may be necessary to repair a torn tendon. Source link

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