How body mass index affects breast cancer risk in postmenopausal women with and without cardiovascular disease

New research suggests that postmenopausal with additional weight heart disease is associated with particularly high risk of growth of breast cancer in women. There are conclusions Published In cancer,

However, there is a known risk factor for the High Body Mass Index (BMI) Breast cancer In postmenopausal women, it is not clear that this risk differs with heart disease or type 2 diabetes and without women. To investigate, a team led by Hanz Freslling of the International Agency for Research on Cancer (World Health Organization), a team led by PhD analyzed 168,547 postmenopausal women analyzed data of cancer and nutrition (epic) and European future probe into the UK biobank, which were not type 2 diabate or cardiovascular diseases when they participate.

Average of 10.7 years in epic and 10.9 years in UK Biobank, 6,793 postmenopausal women Developed breast cancer. In a pool analysis of both studies, every 5 kg/m² The increase in BMI was associated with 31% higher risk of breast cancer in women who developed heart disease during follow -up and 13% higher risk in women without heart disease. Type 2 diabetic development did not affect the risk of breast cancer: with or without type 2 diabetes The risk of breast cancer related to high BMI was equally elevated.

Combination of overweight (BMI ≥ 25 kg/m²) And cardiovascular disease Compared to estimates, 153 more cases of breast cancer per year were estimated to lead more cases per year.

“The findings of this study can be used to inform risk-circulated breast cancer screening programs,” Dr. Fesleing said. “This study should also inspire future research to involve women with the history of heart diseases in weight loss tests for the prevention of breast cancer.”